The low affinity these acidic forms have for the CB1 and CB2 receptors of the endocannabinoid system makes them non-psychoactive. For cannabinoids to acquire psychoactive effects, they must undergo decarboxylation.
This process removes the carboxyl group by applying heat, consequently releasing CO2 and resulting in the neutral, psychoactive form.
Decarboxylation can occur naturally when the plant is exposed to the sun for a prolonged period, but it can also be accelerated in industrial settings. It is crucial to control temperature and time to achieve effective decarboxylation.
Among the most important cannabinoids, we find Tetrahydrocannabinol (THC): the predominant psychoactive component in psychoactive varieties.
CBD is another fundamental component of the cannabis plant. Its presence varies between strains, being minimal in some and more abundant in others.
The percentages of THC in psychoactive strains vary depending on their type and growing conditions, ranging from low to over 25% THC. According to international regulations, non-psychoactive varieties, known as hemp, must contain less than 0.3% THC.
There are several cannabinoids with psychoactive effects, including THC, cannabinol, and delta-8-THC, with THC being the most potent and abundant. Most people seek these cannabinoids for adult or recreational purposes.
On the other hand, other cannabinoids, such as CBD and CBG, are not psychoactive, although they have an affinity for the central nervous system and exert their actions on it. In fact, CBD counteracts the psychotomimetic effects of THC.
Despite strict regulation of THC due to its effects on memory and perception, its therapeutic properties are backed by science. In certain clinical conditions, its effects on proprioception and memory can be beneficial, such as in the treatment of pain and post-traumatic stress disorder.
THC has shown potential in various medical applications, including:
Used in specific medical treatments.
Unlike THC, CBD does not produce psychotropic effects, although it does act on the central nervous system. In fact, CBD counteracts the psychotomimetic effects of THC and is characterized by its wide therapeutic margin and mild side effects in a wide range of doses.
El CBD ha sido ampliamente estudiado por su potencial en diversas aplicaciones médicas, incluyendo:
CBD is not only used for therapeutic purposes, but is also recommended as a food supplement in certain countries.
CBD’s excellent tolerance and broad spectrum of benefits make it a promising option for wellness and health.
We develop natural, safe, and science-backed products to treat chronic pain, anxiety, and neurological disorders. Our approach goes beyond product development: we lead clinical studies in Brazil and Australia to validate new therapies for insomnia and Rett syndrome.
We develop natural, safe, and science-backed products to treat chronic pain, anxiety, and neurological disorders. Our approach goes beyond product development: we lead clinical studies in Brazil and Australia to validate new therapies for insomnia and Rett syndrome.
